What is Tience?

Tience® is a breakthrough innovation in regenerative aesthetics. Backed by decades of research, it is used to treat aging skin and skin defects by stimulating the skin’s natural capability to heal.

Tience is the first product that is able to harness the excellent regenerative and reparative potential of human subcutaneous adipose tissue, offering treatment that aims for younger and healthier skin naturally.

The skin-regenerating power of subcutaneous fat

In the early 2000s, a breakthrough occurred in regenerative medicine. As fat grafting (or fat transfer) became more common, it was observed that adipose tissue has a surprising, positive effect on skin condition. This observation initially emerged as a chance discovery: skin lesions such as scars in the treated areas healed significantly faster, both in appearance and function. However, the real surprise came when fat grafting was started on the face. The tone, structure and elasticity of aged skin improved as if by itself. Since then, numerous research groups around the world have studied the properties of fat grafting. Although the results are revolutionary, fat grafting has clear limitations. Fat grafting is an expensive and difficult surgical process that is performed in an operating room. In addition, fat cannot be transferred from one person to another.

The result of Finnish product development

So where does the skin-regenerating power of adipose tissue come from? According to research, the skin-regenerating power of adipose tissue comes from its bioactive ingredients. These serve like a first aid unit in the skin: they accelerate skin healing and guide the formation of new, healthy skin.

Linio Biotech’s research has focused on understanding whether skin-repairing bioactive substances can be isolated without fat cells and developed into a treatment that is accessible to everyone. We set out to answer this question more than 15 years ago. After thorough research, we succeeded in doing what many thought was impossible: We isolated the regenerative power of adipose tissue to create a ready-to-use treatment.

The name of our innovation is Tience®. As a unique achievement in tissue science and technology it aims to revolutionize our conception of skin care.
Find Tience Clinics

What makes the Tience treatment unique?

As people age, their skin undergoes several changes that slow down its natural ability to renew itself. Cell count decreases, metabolism slows down, and skin vitality wanes. But could we turn time backwards and restore the bright freshness of youthful skin?

Tience’s unique formula can help boost the skin’s own healing processes, allowing damaged skin to repair itself more effectively and faster. The goal of the treatment is not just a beautiful appearance, but the functional well-being of the skin. Tience® acts as a biostimulator and affects many processes, such as tissue regeneration, the healing of skin damage, and blood vessel formation. The product’s molecules create an optimal microenvironment in the areas where they are administered, and can trigger the skin’s natural renewal process.

The bioactive ingredients in Tience comprehensively control the production of the skin’s own repair tools, such as collagen, elastin, and hyaluronic acid. Tience has been shown to activate fibroblasts and stimulate the formation of collagens I, III, and IV, as well as hyaluronic acid.

How do they help the skin?

1.

Fibroblasts produce collagen, elastin and other components of the extracellular matrix that maintain the structure and elasticity of the skin and repair damaged tissue.

2.

Collagen I: The most common type of collagen, forming strong fibers and supporting the structure and durability of the skin.

3.

Collagen III: Often occurs together with collagen I and particularly supports the elasticity of the skin. It plays an important role in tissue healing.

4.

Collagen IV: Forms a reticular structure and is a key part of the basement membrane, which supports the surface layer of the skin and ensures its strength.

When it comes to the long-term impact of the treatment, the essential Tience® feature is the capacity to support local microcirculation. Improved microcirculation brings oxygen and nutrients, activating cells in all layers of aging skin. Tience nourishes the skin with lipids that moisturize it and strengthen the surface layer of the skin.

Tience not only advances keratinocyte proliferation and skin surface renewal, but also activates mesenchymal stem cells. They promote tissue repair and regeneration in damaged tissues, and regulate inflammatory and immune responses.

The effects of Tience may lead to improved skin function and reduced signs of aging. Results may vary from one individual to another.
Find Tience Clinics

Tience’s mechanism of action

Regenerative Aesthetics

Regenerative Aesthetics is an emerging field of regenerative medicine, with various methodologies focused on skin regeneration. Regenerative medicine aims to repair and regenerate damaged tissues and organs, while regenerative aesthetic treatments activate the skin’s own regenerative ability by utilizing the body’s natural functions and help maintain the skin’s youthful appearance. The field of regenerative aesthetics offers alternatives to traditional surgical methods that are less invasive and laborious, and these will usually shorten recovery time and reduce potential risks.

Usage

Tience is introduced into the skin area to be treated either by means of small injections or it is applied superficially, for example in conjunction with microneedling or laser therapy. Tience treatments are performed only by nurses and doctors trained in the use of the Tience product.
Find Tience Clinics

Product description

Tience® is an injectable product supplied in a 1.5 ml ampoule. Tience contains over a thousand different constituents, such as proteins, peptides, lipids and antioxidants; these act as the building blocks for the skin, protect the skin and activate skin cells, improving skin functionality.

Patented Technology
Clinically Tested
Scientifically Proven
Made in Finland